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Results for " HY-P1221A " in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Area
  • HY-P1221A
    ProTx II TFA Sodium Channel Neurological Disease
    ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors[1][2].

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